The Department of Health and Social Care (DHSC) has issued a medicine supply notification for the following products:

  • Humulin® I (insulin isophane human) 100units/ml suspension for injection 10ml vials
  • Humulin® M3 (insulin isophane biphasic human 30/70) 100units/ml suspension for injection 10ml vials
  • Humalog® Mix25 (insulin lispro biphasic 25/75) 100units/ml suspension for injection 10ml vials
  • Humulin® S (insulin soluble human) 100units/ml solution for injection 10ml vials

MSN/2025/045

Tier 2 – medium impact

Date of issue: 23/07/2025

  • Vials of Humulin® I, Humulin® S, Humulin® M3, and Humalog® Mix25 are being discontinued
  • Supplies of Humulin® I and Humalog® Mix25 vials are anticipated to be exhausted by the end of April 2026; and Humulin® M3 and Humulin® S vials by the end of May 2026.
  • Humulin® I, Humulin® S, Humulin® M3, and Humalog® Mix25 in cartridges (for use with HumaPen® Savvio® reusable pen) remain available, and can support increased demand (see Supporting information).
  • Humulin® I, Humulin® M3 and Humalog® Mix25 in disposable KwikPens® remain available and can support increased demand (see Supporting information).
  • Insulatard® (insulin isophane human) 100units/ml suspension for injection and Actrapid® (insulin soluble human) 100units/ml solution for injection 10ml vials remain available but cannot support increased demand.

A copy of this medicine supply notification, including actions required and supporting information, has been sent to all pharmacy NHS email addresses.

DHSC and NHSE/I have now launched an online Medicines Supply Tool, which provides up to date information about medicine supply issues. The contents of these MSNs can now be viewed on the Tool.

The Tool also details any changes to resupply dates and updates to the entries.

To access the Tool, you will need an NHS email address. Once set up and logged in, you will be able to access it online.

New shortages not listed on the SPS website can be reported using our shortage reporting tool.

The post Medicine Supply Notification: Vials of Humulin® I, Humulin® S, Humulin® M3, and Humalog® Mix25 are being discontinued. appeared first on Community Pharmacy England.